Ottawa, October 29, 2022 (GLOBE NEWSWIRE) – World Immune Inspection Inhibitors Market Size It reached $31.4 billion in 2021. The immune system’s job is to protect healthy body cells from invading foreign matter (such as bacteria and cancer cells). Immunotherapy, which includes checkpoint inhibitors, is effective in treating cancers such as lung cancer and melanoma. When immune cells called T cells have certain proteins on their surface, immune checkpoints (recognizers) are activated. These checkpoints also interact with companion proteins in other cells, such as malignant cells. As a result, these cells help prevent the immune system from eliminating cancer.
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Cancer areas are treated with radiation and surgery, and the field of oncology is broad and includes a variety of application areas. Chemotherapy usually spreads through the bloodstream to treat patients’ entire bodies, and this is referred to as systemic therapy. Treating cancer cells helps patients’ immune systems to fight cancer more successfully. Cancer is the leading cause of death in the world. Thus, immune checkpoint inhibitors prevent the growth of cancer cells and help in their detection by the immune system or cells.
Immune cells that must be activated and inactivated in order to initiate the immune response and prevent infection of the immune system are targeted with immune checkpoint inhibitor drugs. In addition, a number of well-known companies are funding clinical development through research and development investments. The checkpoint inhibitor pembrolizumab was the first FDA-approved drug based solely on the presence of a genetic characteristic in a tumor, used to treat MSI-H and dMMR cancers. Immune checkpoint inhibitors are a growing market due to the ongoing competition in the industry.
North America dominated the market in 2021 due to the growing number of oncology patients. Expanding the development of new drugs to treat cancer is getting more money and support from the government. In addition, the increase in research and development of new and innovative drugs in the market is aiding regional growth. The market for immune checkpoint inhibitors is expanding as a result of government support for the development of new cancer drugs.
- The North American market captured 47% of the market share in 2021.
- By type, the PD-L1 inhibitor segment captured 64% of the market share in 2021 and is growing at a compound annual growth rate of 16.8%.
- By application, the lung cancer segment captured 37.5% of the market share in 2021.
- By region, the Asia Pacific region is poised to grow at a compound annual growth rate of 18.4% from 2022 to 2030.
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|Market size in 2030||148.1 billion US dollars|
|compound annual growth rate||6.91% from 2022 to 2030|
|biggest market||North Amarica|
|The fastest growing region||Asia Pacific|
|prediction year||2022 to 2030|
|The main players||AstraZeneca PLC, Eli Lilly and Company (ARMO Biosciences.), Bristol-Myers Squibb Company, Roche Holding AG, Incyte Corporation, Novartis AG, GlaxoSmithKline PLC, F. Hoffmann-La Roche Ltd. (Genentech Inc.,), Sanofi, Merck & Co., Inc., Merck KGaA (EMD Serono Inc.), BeiGene Ltd, Shanghai Jhunsi Biosciences Ltd.|
Market dynamics of the immune checkpoint inhibitors market
- Immune checkpoint inhibitors are a growing market due to the ongoing competition in the industry. The immune checkpoint inhibitors market is expanding due to factors such as adoption of unhealthy lifestyle, rise in cancer cases, genetic mutations and changes that have an impact on the cost of healthcare in the country.
- Additionally, rising healthcare costs in this market, increasing use of immune checkpoint inhibitor drug in emerging regions, and technical advances in cancer screening and broadcasting methods are all factors driving the growth of the immune checkpoint inhibitor industry.
- However, the high cost of product research and development subsequently raises the price of the final product and related treatments, a factor that is expected to limit market growth for immune checkpoint inhibitors.
- In addition, regulatory price restrictions resulted in higher prices for immune drugs at the checkpoint. It is also expected that the regulatory price ceiling for immune checkpoint inhibitors may hamper market expansion.
- The immune checkpoint inhibitors market is also being restricted by the development of cancer treatment technology and increasing public awareness of immune system disorders.
- In order to advance their research projects, worldwide players in the immune checkpoint inhibitor market frequently collaborate with companies that combine their core capabilities. For example, Merck, known as MSD outside the United States and Canada, and Dynavax Technologies Corporation are investigating the potential synergistic effects of combining SD-101 from Dynavax with Keytruda and MK-1966, two Merck immunotherapies.
- The increasing need for cancer treatments, expansion of research and development projects, and increased reimbursement practices offered by manufacturers and insurers in some countries are important drivers of global market expansion.
End user insight
Hospitals, specialty clinics, academic and research institutions constitute the three end user segments of the global immune checkpoint inhibitors market. Owing to its large customer base, rising healthcare costs, and rising incidences of cancers like lung and bladder cancer, melanoma, Hodgkin lymphoma, etc., the Hospitals & Specialty Clinics segment is expected to hold the largest market share in the global immune checkpoint inhibitors market during the period expectations.
Insight indicator of disease
Lung cancer represents a large part of the disease indicators in general. Advanced forms of lung cancer are targeted with immune checkpoint inhibitor drugs. FDA-approved immune checkpoint inhibitors for the treatment of lung cancer, including ipilimumab, nivolumab, atizolizumab and durvalumab, are fueling the market expansion. In addition, due to the increase in the incidence of bladder cancer, the bladder cancer segment is expected to grow at the fastest rate during the forecast period.
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- Pembrolizumab (KEYTRUDA), for which Merck received rapid approval from the USFDA in June 2019, is likely to increase the company’s market share during the forecast period used to treat patients with metastatic SCLC who have progressed on or after platinum-based chemotherapy and on Least last line of treatment.
According to the type of medicine
- CTLA-4 inhibitor
- PD-1 . inhibitor
- PD-L1 inhibitor
According to disease index
- Lung Cancer
- Bladder Cancer
- skin cancer
- Hodgkin lymphoma
by end users
- Specialty Clinics
- Academic and research institutions
- North Amarica
- Asia Pacific
- Latin america
- Middle East and Africa (MEA)
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